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Genetic variant associated with absence of COVID-19 symptoms


09 Aug 2023

At least 20% of people infected with SARS-CoV-2, the virus that causes COVID-19, never showed symptoms. These asymptomatic infections could provide clues to how the virus can be quickly cleared from the body. Genetic factors may be involved. However, most studies of genetics and COVID-19 outcomes to date have focused on severe disease.


Delivering Extra Protection Against COVID-19


27 Jul 2023

What you need to know SARS-CoV-2, the virus that causes COVID-19, is covered in spike proteins. These spike proteins interact with a protein called angiotensin-converting enzyme 2 (ACE2) that sits on the surface of human cells. By attaching to ACE2, the virus can infect the human cells. Because ACE2 does not change, the part of the spike protein that interacts with ACE2 is unlikely to change or mutate. This makes the development of “decoy” ACE2 proteins — proteins that bind to SARS-CoV-2 before it can attach to human cells — a promising target for new treatments.


What Long COVID Looks Like in Children and Young Adults


22 May 2023

At least 15 million kids have been infected with SARS-CoV-2, the virus that causes COVID-19, but it is unclear how many of them have had or are living with long COVID. The ailment includes symptoms that linger after COVID-19 or symptoms that come back after an absence of weeks or months. A person might feel short of breath, lose their sense of smell, be unable to think clearly, be tired all the time, or have other maladies that can be traced back to COVID-19.


Rapid Progression of Dementia Following COVID-19


03 May 2023

What you need to know COVID-19 can cause long-term problems with thinking, concentrating, and remembering. This condition is commonly known as “brain fog.” Brain fog after COVID-19 has been studied mostly by observing previously healthy people. In a small study supported by the National Institute of Neurological Disorders and Stroke (NINDS), researchers examined the cognitive impact of COVID-19 on people with dementia. The researchers found that having COVID-19 rapidly accelerated the structural and functional brain deterioration of patients with dementia, regardless of the type of dementia being experienced.


Symptoms of Long COVID Differ for People of Different Racial and Ethnic Groups


06 Apr 2023

What you need to know As the COVID-19 pandemic continues, a growing number of people are experiencing long-term symptoms and health problems following SARS-CoV-2 infection, a condition known as Long COVID. However, the likelihood of being diagnosed with Long COVID seems to vary. A study supported by the Researching COVID to Enhance Recovery (RECOVER) Initiative found that the majority of patients from a sample of more than 30,000 patients with a Long COVID diagnosis were White, non-Hispanic, female, and likely to live in more affluent areas with greater access to health care. Because the COVID-19 pandemic has disproportionately affected people from racial and ethnic minorities, this finding may mean that people from those groups are living with Long COVID without a formal diagnosis.




Articles


Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination


04 Feb 2021

We recently reported the results of a phase 1 trial of a messenger RNA vaccine, mRNA-1273, to prevent infection with SARS-CoV-2; those interim results covered a period of 57 days after the first vaccination.




How the Novavax Vaccine Works


03 Feb 2021

The Maryland-based company Novavax has developed a protein-based coronavirus vaccine called NVX-CoV2373. The vaccine produced strikingly high levels of antibodies in early clinical trials.




Evaluation of Cloth Masks and Modified Procedure Masks as Personal Protective Equipment for the Public During the COVID-19 Pandemic


19 Jan 2021

Severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2), the cause of coronavirus disease 2019 (COVID- 19), is a transmissible virus that infects the upper and lower respiratory tract, leading to a high viral titer in saliva and respiratory secretions.




COVID-19 as the Leading Cause of Death in the United States


12 Jan 2021

The current exponential increase in coronavirus dis- ease 2019 (COVID-19) is reaching a calamitous scale in the United States, potentially overwhelming the health care system and causing substantial loss of life.




Feds Authorize $22 Billion to Boost Vaccine Rollout


11 Jan 2021

The CDC will send $3 billion to the states to boost a lagging national COVID-19 vaccination program.




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