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Biomedical Research Leads Science’s 2021 Breakthroughs


04 Jan 2022

Breakthrough of the Year: AI-Powered Predictions of Protein Structure The biochemist Christian Anfinsen, who had a distinguished career at NIH, shared the 1972 Nobel Prize in Chemistry, for work suggesting that the biochemical interactions among the amino acid building blocks of proteins were responsible for pulling them into the final shapes that are essential to their functions. In his Nobel acceptance speech, Anfinsen also made a bold prediction: one day it would be possible to determine the three-dimensional structure of any protein based on its amino acid sequence alone. Now, with advances in applying artificial intelligence to solve biological problems—Anfinsen’s bold prediction has been realized.


The F.D.A. clears booster shots for 12- to 15-year-olds


03 Jan 2022

The Food and Drug Administration on Monday authorized booster doses of Pfizer-BioNTech’s coronavirus vaccine for 12- to 15-year-olds, a group that became eligible for initial shots in May.


Expecting a Surge; We look at the latest on Omicron.


16 Dec 2021

Get ready for the Omicron surge, and take it seriously. But remember that the vaccines appear to provide strong protection against what matters most: severe Covid illnesses. That’s my reading of experts’ reactions to the latest developments on the Omicron variant. Today, I will walk through them.


Latest on Omicron Variant and COVID-19 Vaccine Protection


14 Dec 2021

There’s been great concern about the new Omicron variant of SARS-CoV-2, the coronavirus that causes COVID-19. A major reason is Omicron has accumulated over 50 mutations, including about 30 in the spike protein, the part of the coronavirus that mRNA vaccines teach our immune systems to attack. All of these genetic changes raise the possibility that Omicron could cause breakthrough infections in people who’ve already received a Pfizer or Moderna mRNA vaccine.


Will the Vaccines Stop Omicron? Scientists Are Racing to Find Out.


28 Nov 2021

A “Frankenstein mix” of mutations raises concerns, but the variant may remain vulnerable to current vaccines. If not, revisions will be necessary.




Articles


Pfizer Vaccine Appears to Work Against Variant, Research Shows


08 Jan 2021

Laboratory experiments indicate the Pfizer/BioNTech vaccine will offer protection against the two coronavirus variants found in the United Kingdom and South Africa.




COVID Likely the Third-Leading Cause of Death in US, CDC Says


07 Jan 2021

COVID-19 was probably the third leading cause of death in the United States during 2020, CNN reported, citing an email from statisticians with the U.S. Centers for Disease Control and Prevention.




Moderna CEO: Vaccine Will Likely Work for 'a Couple of Years'


07 Jan 2021

The Moderna vaccine ― one of two vaccines now being distributed in the United States ― will "potentially" provide protection against COVID-19 for several years, the biotech company's CEO said, according to Reuters.




Over Half of COVID Transmission May Occur via Asymptomatic People


07 Jan 2021

As COVID-19 cases surge and vaccinations lag, health authorities continue to seek additional ways to mitigate the spread of the novel coronavirus.




SARS-CoV-2 Transmission From People Without COVID-19 Symptoms


07 Jan 2021

IMPORTANCE Severeacuterespiratorysyndromecoronavirus2(SARS-CoV-2),theetiologyof coronavirus disease 2019 (COVID-19), is readily transmitted person to person. Optimal control of COVID-19 depends on directing resources and health messaging to mitigation efforts that are most likely to prevent transmission, but the relative importance of such measures has been disputed.




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